14th Annual Maternal and Child Health Epidemiology Conference December 10-12, 2008 Crowne Plaza Hotel Atlanta - Ravinia
Atlanta, GA

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Article Alert: Fetal Exposure to Alcohol as Evidenced by Fatty Acid Ethyl Esters in Meconium ...

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Fact: 58.8% of women of child bearing age (15-44) consume alcohol, whether or not they are using contraceptives


p r e v e n t i n g   a l c o h o l - e x p o s e d   p r e g n a c i e s

CDC supports the following prevention activities:

 

Reducing Alcohol-Exposed Pregnancies Through the Use of Community-Level Guided Self-Change Programs
Community resources for assisting individuals who are problem drinkers but who are not alcohol-dependent are limited in most communities. Over the past decade, increasing attention has been directed toward programs focused on engaging the individual’s own capacity for self-change as a means of achieving recovery from alcohol problems. This approach is supported by findings that up to 75% of individuals who change their problem drinking habits do so without the use of formal treatment programs. Guided self-change (GSC) programs tend to be of low intensity as compared with traditional treatments, targeted toward the community at large, and focused on problem drinkers as opposed to severely alcohol-dependent drinkers. The goal of these programs is to attract and assist motivated individuals in the early stages of alcohol abuse to take part in an intervention aimed at facilitating a client-driven, self-change process of alcohol reduction or abstinence. GSC intervention components are similar to those of brief interventions and include personal feedback, advice, goal-setting, and self-monitoring of behavior reformatted into self-administered materials that can be completed at home.

In 2004, CDC funded two universities to 1) develop, implement, and evaluate community-level, self-guided change projects targeting women 18 to 44 years of age who are at risk for an alcohol-exposed pregnancy; and 2) demonstrate a 15% reduction in the proportion of women at risk for an alcohol-exposed pregnancy in community-based intervention sites as compared with non-intervention community-based sites.

FUNDED PROJECTS

Nova Southeastern UniversityFt. Lauderdale, Florida
An intervention will be instituted for a sample of women 18 to 44 years of age who are at risk for an alcohol-exposed pregnancy in three counties in south Florida. Participants will be recruited through the media (e.g., newspaper advertisements, mail flyers, television, billboards, and radio public service announcements). Once respondents are screened and determined to be eligible, they will be randomly assigned either to a motivational intervention promoting self-change, or to a control intervention that will provide information only about the risk of fetal alcohol syndrome. The intervention group will receive a one-time mailing about how to either reduce alcohol consumption or increase use of effective birth control. Women who are unsuccessful at reducing their risk can access professional services for help. The specific goals of the study are to 1) determine the degree to which participants decrease their risk for an alcohol-exposed pregnancy, and 2) determine the level of use of professional resources for self-change. The efficacy of the intervention will be evaluated and the results will be disseminated to health care providers in the local community. For more information about the program at Nova Southeastern University, contact the Guided Self-Change Clinic at (954) 262-5968 or visit their web site at http://www.nova.edu/gsc.

St. Louis University
St. Louis, Missouri
A community-based self-change project will be conducted with the goal of reducing the risk of alcohol-exposed pregnancies by 15% among African-American women in St. Louis. St. Louis has a high number of childbearing age women in an at-risk community, with a high prevalence of binge drinking that continues during pregnancy. Kansas City is the comparison community. Baseline risk for alcohol-exposed pregnancies in both St. Louis and Kansas City will be assessed using a random digit dial survey. Behaviors relating to both alcohol use and contraceptive use will be assessed. Recruitment of participants will take place through advertisements in the media, through the random digit dial survey, and through health care provider offices and WIC clinics. Educational materials about reducing at-risk drinking or increasing proper use of birth control will be mailed to participants, but will also be available through the Internet. These materials will guide participants through a self-change process. Follow-up will occur 4 months after enrollment.

 

Project CHOICES
(Changing High-Risk AlcOhol Use and Increasing Contraception Effectiveness Study) Preventing Alcohol-Exposed Pregnancies Among High-Risk Women in Special Community-Based Settings

In September 1997, CDC awarded cooperative agreements to three university grantees to develop brief interventions aimed at preventing alcohol-exposed pregnancies among women of childbearing age in special settings. The selected settings have access to relatively large numbers of women of childbearing age who drink at high-risk levels and do not use contraception effectively. The grantees, along with the special settings they are working in, are:

Nova Southeastern University in Ft. Lauderdale, Florida

Adult and Pediatric Primary Care Centers in the North Brossard Hospital District of Ft. Lauderdale

Recruitment of a cohort of women concerned about problem drinking through media advertisement in the Ft. Lauderdale area

University of Texas Health Sciences Center at Houston, School of Public Health in Houston, Texas; Harris County Jail; Houston Recovery Campus

Virginia Commonwealth University, Medical College of Virginia in Richmond, Virginia; Gynecology Outpatient Clinic of the Medical College of Virginia; South Richmond Health Center

Funded grantees worked collaboratively with one another and CDC to develop a uniform study protocol for implementation in the six special settings. The objectives of the study are to:

Characterize the women in the special high-risk settings.

Reduce the rate of alcohol consumption among women who are not using contraception effectively and increase contraception effectiveness among women who do not reduce their alcohol consumption.

Examine the relationship between selected process variables and study outcomes.

An epidemiologic survey, administered to approximately 500 women in each of the six settings, was conducted during the first phase of the study. The purpose of the survey is to characterize the overall population in the special settings in terms of prevalence and patterns of alcohol use, prevalence of characteristics associated with heavy alcohol use, reproductive health status (for example, parity, contraceptive practices, current sexual activity, and fertility), alcohol treatment histories, and history of psychiatric illnesses. To get more information about the Project CHOICES epidemiologic survey findings, click here: PROJECT CHOICES.PDF

A common protocol for a behavioral intervention was developed, implemented, and evaluated in each of the six settings. A feasibility study designed to test the behavioral intervention was conducted from March 2000 until May 2001. Study participants (50 women from each of the six special settings) were provided a brief intervention of four sessions delivered over the course of eight weeks. The intervention consists of the following:

In-depth assessment of alcohol use and contraceptive use patterns.

Counseling about the consequences of alcohol use during pregnancy.

Brief advice and counseling for moderate-to-heavy drinkers to reduce intake levels, or referral to community treatment services for alcohol-dependent drinkers.

Reproductive health education about contraceptive methods, provision of contraceptive services, and client follow-up.

Click here to get more information about the Project CHOICES feasibility study: MI PROJECT CHOICES.PDF

The next phase of Project CHOICES will assess the efficacy of this behavioral intervention further in a scientifically rigorous manner (through a randomized control group design). This phase began in June 2002 and is expected to be completed by June 2004.


Project BALANCE
(Birth Control and ALcohol Awareness: Negotiating Choices Effectively)
Preventing Alcohol-Exposed Pregnancies in Adolescents

Many young women in the United States who drink alcohol and have unprotected sex are putting themselves at risk for an alcohol-exposed pregnancy. Not much is known about the relationship between moderate-to-heavy alcohol use, unprotected sex, and unplanned pregnancies in young women. Well-designed epidemiological and behavioral studies are needed to better understand and intervene with this population. The following project is exploring these issues.

FUNDED PROJECTS
Virginia Commonwealth UniversityRichmond, Virginia
Project BALANCE consists of (1) a brief epidemiologic survey, (2) focus groups, and (3) a randomized, controlled trial of a motivational intervention directed at Virginia Commonwealth University (VCU) college students from 18 to 24 years of age. The proposed intervention is a modified form of Project CHOICES, a pre-conceptional, motivational intervention designed collaboratively with CDC and three institutions, of which VCU is one. Project BALANCE’s objectives are to identify the prevalence of risky drinking and contraceptive behaviors in this population, and to test the efficacy of an intervention in a randomized trial comparing a group receiving both assessment and one face-to-face session with a group receiving assessment only. A brief survey is being administered to college women to identify those eligible for intervention and to further characterize the population. Focus groups with college women are also underway to explore qualitative issues related to drinking, contraception, and sexual behavior. The intervention focuses both on drinking and unprotected sex, allowing a woman to modify either or both behaviors. Follow-up will occur at 1 month and 4 months.


Preventing Alcohol-Exposed Pregnancies in Diverse Populations
Rates of harmful drinking among women from diverse populations and the characteristics of those at greatest risk are not well understood. Well-designed epidemiologic studies are needed to better understand these populations of women. Likewise, intervention studies aimed at reducing the risk of alcohol-exposed pregnancies need to be designed and evaluated to determine the most effective approaches for high-risk women from diverse populations. The following projects were funded to address this issue.

FUNDED PROJECTS
San Diego State UniversitySan Diego, California
This project’s goal was to (1) determine the frequency of self-reported alcohol consumption in a sample of low-income pregnant and non-pregnant Latinas of childbearing age and examine risk factors for alcohol use, and (2) test the effectiveness of an educational feedback intervention among non-pregnant Latinas on intent to change alcohol consumption behaviors in a future pregnancy. Screening questionnaires and in-person interviews provided information on the women and their use of alcohol. The intervention group received educational feedback on their self-reported current consumption. The intervention assessed intention to reduce current alcohol consumption and/or avoid alcohol use in a future pregnancy. Outcomes regarding future intentions were measured through a post-intervention telephone interview 3 months following the baseline interview. Click here to find more information about the project’s findings regarding alcohol consumption among low-income, pregnant Latinas: ALCOHOL AMONG LATINAS.PDF

University of Texas at San AntonioSan Antonio, Texas
This project explored characteristics regarding alcohol use and pregnancy, and tested the effectiveness of a social action approach to prevent alcohol-exposed pregnancies among Latinas in San Antonio. The project investigated the values, attitudes, and behaviors of Latinas regarding motherhood and pregnancy, patterns of alcohol use and familial patterns, sexual activity, and knowledge of fetal alcohol syndrome. The study pilot tested a social action intervention model that aims to alter normative drinking behavior and/or sexual behavior. Quantitative measures were used to determine differences in knowledge, attitudes, and behaviors and qualitative methods were used to understand the interplay between individual and social change. Follow-up was conducted 6 months after the intervention.


Increasing Public Awareness of the Risks of Alcohol Use During Pregnancy Through Targeted Media Campaigns
Effective media campaigns create awareness, change attitudes, and motivate individuals and communities to engage in healthy behaviors. Successful campaigns target specific audiences taking into account the unique preferences and needs of particular groups. The targeted media campaign is one strategy to enhance current prevention efforts related to fetal alcohol syndrome (FAS) and other prenatal alcohol-related effects. Evidence-based approaches to the design, implementation, and evaluation of these types of projects are needed and are currently underway to determine the most effective strategies for use in media campaigns aimed at reducing prenatal alcohol use.

FUNDED PROJECTS

St. Louis University
St. Louis, Missouri
This project is designing, implementing, and evaluating a media campaign targeting African-American women, aged 18 through 35 years, at risk for pregnancy. The primary purpose of the campaign is to increase knowledge and change attitudes about alcohol use during pregnancy. A comprehensive media campaign has been developed using a variety of strategies including visual, audio, and print advertisements, direct marketing, media interviews with experts, and community event exposure. The campaign is built around four core messages: (1) drinking alcohol during pregnancy harms unborn babies, (2) pregnant women should abstain from alcohol, (3) sexually active women should not drink if they could be pregnant, and (4) women at risk for an alcohol-exposed pregnancy should see a physician. Evaluation of the intervention consists of pre- and post-intervention random-digit dialing surveys of the African-American community both in St. Louis and Kansas City (control group).

University of California at Los AngelesLos Angeles, California
This project is developing, implementing, and evaluating a social marketing campaign using a “narrowcasting approach” that warns women about the dangers of drinking alcohol during pregnancy. Narrowcasting refers to information that is directed to a highly specific segment of the public. The purpose of the project are to change norms and perceptions of women who are light or moderate drinkers both prior to and during pregnancy. The target groups include White, Hispanic, and African-American women, aged 18 through 30 years. Print materials have been developed and disseminated, saturating specific neighborhoods in two communities of southern California over a 12-month period, with a third community serving as a comparison group. Project partners work with community participants and professional agencies to create high-quality campaign messages and materials. Evaluation consists of a repeated cross-sectional survey design.

University of IowaIowa City, Iowa
The goals of the project are to design, implement, and evaluate the effectiveness of a broad-based and localized media campaign aimed at reducing prenatal alcohol use in rural areas, targeting women enrolled in the Women, Infants, and Children (WIC) program. Through formative research, project staff are producing commercial-quality materials for dissemination in three channels (a broad based 30-second television commercial, a eight minute video for localized distribution in WIC clinics, and a printed pamphlet for distribution in WIC clinics) to increase awareness about the dangers of alcohol use during pregnancy. WIC clinics in rural Iowa will be paired and randomly assigned to usual-care or intervention groups. The usual-care group will be exposed to the 30-second commercial and printed pamphlet, while the intervention group will be exposed to messages in all three channels. Evaluation will consist of pre- and post-test surveys assessing changes in knowledge, interactions with health care professionals, reported alcohol use, and perceptions of normative expectations in the social network regarding consumption of alcohol during pregnancy.

 

Enhancing Clinical Practices to Prevent Alcohol-Exposed Pregnancies
In 2004, 11.2% of pregnant women aged 15 to 44 reported alcohol use and 4.5% reported binge drinking. Among nonpregnant women of childbearing age, 52.8% reported alcohol use and 23.3% reported binge drinking. Half of all pregnancies are unplanned, and many women will not know they are pregnant during the early weeks of gestation and may continue drinking. Identifying women who are at high risk for an alcohol-exposed pregnancy and intervening with them before conception (or at least as early as possible thereafter) is an essential strategy for preventing alcohol-exposed pregnancies.

FUNDED PROJECT

American College of Obstetricians and GynecologistsWashington, D.C.
To address the prevention of alcohol-exposed pregnancies, the American College of Obstetricians and Gynecologists (ACOG), in collaboration with CDC’s Fetal Alcohol Syndrome Prevention Team, is developing educational materials and practice tools for women’s health care providers. These materials will guide providers to screen, educate, and intervene with women who are at risk for an alcohol-exposed pregnancy. These materials will include brief background research and information, the components of brief interventions, harm-reduction messages, and resource and referral information. They will be packaged as a short provider’s guide, available both in print and on CD-ROM, and as a pocket card with information to prompt the clinician for screening and intervention. The information in the guide will also be available for downloading on the ACOG website. An advisory committee, made up of obstetrician/gynecologists, content experts, CDC staff, and others, is guiding the development and distribution of these materials. The materials should be available in mid-2006.


Improving Community-Based Fetal Alcohol Syndrome Prevention Efforts Using the
Fetal and Infant Mortality Review Methodology

Prenatal exposure to alcohol is one of the leading preventable causes of birth defects, mental retardation, and neurodevelopmental disorders in the United States. One of the national health objectives for 2010 is to increase the percentage of pregnant women abstaining from alcohol from 86% to 94%. According to national data collected in 2002 by the Behavioral Risk Factor Surveillance System, 10% of women reported drinking alcohol during pregnancy. CDC studies have documented fetal alcohol syndrome (FAS) prevalence rates ranging from 0.2 to 1.5 per 1,000 live births.

FUNDED PROJECT

American College of Obstetricians and GynecologistsWashington, D.C.
The National Fetal and Infant Mortality Review Program (FIMR) is a collaborative effort between the American College of Obstetricians and Gynecologists and the Maternal and Child Health Bureau, Health Resources and Services Administration. FIMR is a community-based program to improve the health and well-being of women, infants, and families.

The goal of this project is to use the established FIMR process to expand the knowledge base about service systems, specifically the personal knowledge, attitudes, and beliefs of women who have experienced a loss that might be associated with infant morbidity and mortality due to prenatal alcohol exposure, and to suggest areas where service system improvements, or enhanced health education, might improve outcomes for future families.

 

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